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Do you have the space?
First and foremost, is there adequate space in your house or apartment to run the business? If you are a one-person-show and your only requirement is a desk and a computer, space will not be an issue. If your business is more complex and you need space for file cabinets, equipment, storage for products and supplies, you will have to estimate how much space you need and where is it going to come from. Just don't assume that your spouse will be willing to give up their garage space for the business.